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Arimidex Or Letrozole?
#11
PLEASE READ author L. Rea's column ( Building The Perfect Beast ) in the JULY 2004 issue of Muscular Development, the whole column is devoted to anti-e's and is accordingly titled,
"Whats the Best Anti-Estrogen ?"
Havbe you given Formestane a thought ? It has many of the properties that you need for PCT and also has a nice little anabolic effect too. I think this guy is brilliant and even if I did'nt like MD, I'd still buy it for his articles. I'm working on buying both of L. Rea's books, but with a 2 yr old baby it's hard to throw down that kind of cash just for a book ( as my wife like to put it ). Ya feel me ? lol

~BB~
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#12
cman34677 Wrote:letro hands down....has some libido sides....but thats it....but to counter that it does spike igf-1 which dex doesn't....actually I'm pretty sure dex suppresses it slightly...

dex def. suppresses it.

Without getting too technical or boring with "science geek" talk, there are basically two types of aromatase inhibitors - type 1 & 2. Below you'll find a list of the most popular and effective aromatase inhibitors on the market today:

Relative Potency of Type 1 & 2 Aromatase Inhibitors
Product Aromatase Inhibition (%)
Aromabolan P.C.T.TM (Formestane) 91.1%
Aromasin (Exemestane) 97.9%
Cytadren (Aminoglutethimide) 90.6%
Arimidex (Anastrozole) 96.7%
Femara (Letrozole) 98.7%

By the looks of it,femara (Letrozole) is the strongest inhibitor.

But, there is a potential problem in that estrogen, and more so estradiol, can trigger GH release from the pituitary gland ... this can effect IGF-1 production AND receptors (negatively OR positively). Take a look at the below chart:

How Various Estrogen Inhibitors & Blockers Effect IGF-1
Product Effect IGF-1
Aromabolan P.C.T.TM (Formestane) Increases 26%
Aromasin (Exemestane) Increases 28%
Cytadren (Aminoglutethimide) Increases 27%
Arimidex (Anastrozole) Decreases 18%
Femara (Letrozole) Increases 24%
Faslodex (Fulvestrant) Decreases 70%
Nolvadex (Tomaxifen) Decreases 23.5%


this from BB.com
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